The greenhouse line from Johnny's, is almost all F1's breed for hybrid vigor. That said, they will probable grow quite well. But seed saving may not come out with what you expected. As far as heirlooms in a greenhouse, I grow Chocolate cherry, Sweet 100s and 1 Millions, Little blond Girl, Green Zebra, Cherokee purple, and the only F1 is SunGold. For space reasons, I grow them in hydroponics.
Hope this helps.
Mad