I've had borers in my plants every year, but still had successful zucchini harvests. Check the vines every day for frass, and the moment you find any dig out the borer by cutting through the vine the long way and squash(!) it. Then pile dirt over the vine at the surgery site.
I've learned that as long as the vine is not completely severed, the plant will continue to grow like nothing happened. And, if I eliminate all the early borers, I don't have any more problems with them as the season progresses.
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