I live in a mobile home and my family has a few more as rentals. The ducting underneath a trailer is typically plastic, flexible stuff and not metal like a house. Now I know why they make house vents out of metal - so the mice won't chew through them and make the ducts into mouse highways. The only thing I have found that works to get rid of them is a "rodent block" poison product. I think Tomcat is one brand. It is a brick that they chew on, and lasts a long time. The mice will be gone in a few days.
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