At the same time would be a bit of a waste.
The problem with mites is that they develop resistance real fast. What the acequinocyl for example doesn't kill, they will make babies which will be more or less resistant. So repeating again after 1 month let's say, will have a much lesser effect and so on. They even say on the bottle max 2 times per year.
So best way is to alternate, at a certain interval (1-2 months?).
You have to note that both of these are chemicals, one shouldn't use more than it has to.
There's also the predatory mites, but they are so very expensive here in Germany, but people say they work quite well if introduced when bad mite population is low.
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