I try to spray my squash vines near the base and as they get larger further up the stem with Sevin every 10 days or after every hard rain. I also mix in a little molasses and dish washing soap. BT doesn't work for me down here on squash borers. I also mulch heavily around the base of each plant. Despite doing all of this I will still eventually lose most of my plants to squash vine borers. I don't know if there is any way to completely stop them with anything that won't also poison you too. I used to split the stem a bit and pull the borers out and bury the damaged part of the stem; but by the time the plant was fully recovered it would usually already have more borers in it.
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